Publications

Since CPRD members have had 107 publications in peer-reviewed international journals, with 28 submitted in 2005-06. The indicators of the co-coordinators and Pharma R&D members are given below.

For 2006 to date, 7 peer reviewed articles in Polyhedron have been submitted for publication, members of CPRD have presented at 8 conferences.

 Item Dr.s Egan
& Walsh 		 Other CPRD
members 
Peer reviewed papers published
Peer reviewed papers submitted
Book Chapters
Oral Presentations
POster Presentations 		 18
6
1
15
31		 89
22
11
25
30

Selection of Key Publications of Pharma R&D Team

  • Synthesis and Antimicrobial Activity of Copper(II) and Silver(I) Complexes of Hydroxynitrocoumarins:X-ray crystal structures of [Cu(hnc)2(H2O)2]×2H2O and [Ag(hnc)] (hncH = 4-hydroxy-3-nitro-2H-chromen-2-one). B. S. Creaven, D. Egan, K. Kavanagh, M. McCann, M. Mahon, A. Noble, B. Thati, M. Walsh. Polyhedron, 2005, vol. 24, issue 8, Pg. 949-957
  • Synthesis, superoxide dismutase mimetic and anticancer activities of metal complexes of 2,2,-dimethylpentanedioic acid (2dmepdaH2) and 3,3- dimethylpentanedioic acid (3dmepdaH2): X-ray crystal structures of [Cu(3dmepda)(bipy)]2.6H2O and [Cu(2dmpeda)(bipy)(EtOH)]2.4EtOH(bipy = 2,2’ bipyridine).M. Devereux, M. McCann, D.O’Shea, A. Kellett, M. Walsh, M. O’Connor, D. Egan, C. Deegan, E. Kiely, V. McKee, D. Naughton, A. Fischer .Bioinorganic Chemistry and Applications, 2006, in press (ms. BCA 51112)
  • Synthesis, X-ray crystal structure, anti-fungal and anti-cancer activity of [Ag2(NH3)2(salH)2] (salH2= salicylic acid). Coyle, B., McCann, M., Kavanagh, K., Devereux, M., McKee, V., Kayal, N., Egan, D., Deegan, C. and Finn G, J. Inorg. Biochem., (2004), 98,1361-1366.
  • Daphnetin induced differentiation of human renal carcinoma cells & its mediation by p38 mitogen-activated protein kinase. Finn, G., Creaven, B.S. and Egan, D.  Biochem. Pharm. 67 (2004) 1779-1788.
  • In vitro anti-tumour effect of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines. B. Thati, A. Noble, B. Creaven, M. Walsh, M. McCann, K. Kavanagh, M. Devereux, D.A. Egan. Cancer Letters (MS: CAN-D-06-00277.
  • Synthesis, characterization and antimicrobial activity of a series of substituted coumarin-3-carboxylatosilver(I) complexes B. Thati, A. Noble, B. Creaven, M. Walsh, M. McCann, K. Kavanagh, D.A. Egan. Inorganica Chimica Acta (Ms.ICA-D-06-00125).